Cellular Orthopedics Blog
The New World of Cell Based Therapy and Orthobiologics
About 15 years ago, an article was published regarding the use of Platelet Rich Plasma for the treatment of arthritis. Prior to that clinical trial, physicians would use hyaluronic acid (rooster comb) in an attempt to diminish the symptoms from an arthritic joint. The...
The New World of Cell Therapy and Orthobiologics: A Needle and Not a Knife, Part 1
My goal is to separate fact from fiction by delivering evidence-based care specifically related to orthobiologics, and contribute to biologics knowledge and application in arthritis and orthopedic conditions. At present, too many patients are navigating the field...
Mesenchymal Stem Cell Treatment Update for Arthritis
There are two clinical, readily available sources of adult mesenchymal stem cells, to the cellular orthopedist; the musculoskeletal building cells that have the potential to stop the progression of arthritis. These cells may reverse the damage, regenerate cartilage,...
Several Unorthodox Requests for Biologic Treatment of Arthritis
Over the past several weeks, patients have presented with interest in biologic treatment of arthritis other than “can you regrow my cartilage?” While cartilage regeneration was initially marketed by stem cell purveyors, it never made physiologic sense unless the...
Regenerative Medicine Fact Check or Cellular Orthopedic Q&A
Question: Dr. Sheinkop, three months ago you did an A2M intervention on a 72- year old athletic man with progressive limitations from an arthritic knee. You reported how he was doing at six weeks, how is he doing at 12 weeks? Answer: Hi. I trust all is well with...
100th Publication on Evidence Based Regenerative Medicine and Cellular Orthopedics
“Article Title: Clinical outcomes and safety of a combined autologous bone marrow concentrate intraosseous and intraarticular injection for knee osteoarthritis at 12 months Journal Title: Journal of Regenerative Medicine Dear Dr. Sheinkop I am pleased to tell you that...
Why We Age and Why We Don’t Have To
Is the subtitle of Lifespan, a book written by David A. Sinclair, PhD, and published by ATRIA BOOKS in 2019. While my weekly blogs are focused on Conservative, Preservative and Restorative measures for osteoarthritis, what if aging itself is a disease and that disease...
A Patient Testimonial for Growth Factors
At times, my blog is based on statistically documented evidence concerning Cellular Orthopedic interventions. To date, that’s how I treat patents, evidence based regenerative medicine. This time though, I found an unsolicited testimonial so compelling that I am...
Your Journey with an Arthritic Joint
Better stated, how do you bridge the gaps in the continuum of joint care from early intervention to joint replacement? Arthritic Joint Pain Management First and foremost, our goal is functional restoration and maintenance, relieving symptoms, and postponing, perhaps...
Alpha 2 Macroglobulin Injections – A2M: A Treatment for Arthritis?
On Wednesday, I am clinically testing Alpha 2 macroglobulin, or A2M. My first patient is the product distributor; he is my guinea pig. Supposedly the injection will stop cartilage breakdown in joints, promote tissue growth and support the overall restoration of an...
What is A2M and Exosomes?
This is a cytokine that may neutralize some of the breakdown molecules in degenerating joints. It is found in the circulating blood plasma. There is a centrifuge on the market that can concentrate Alpha 2 Macroglobulin (A2M) from blood, and many doctors who use it...
Regenerative Medicine, Stem Cells, and Orthobiologic Update
We certainly are living in changing times and daily uncertainties, but my practice continues. Over the years, I have noted that when there is public angst, I have a bit freer time to review our outcomes. Alfred E. Neuman, the mascot for Mad Magazine during its heyday,...