As we statistically analyze our Outcomes data, in preparation for presentation at 2015 Regenerative Medicine Meetings, it becomes increasingly apparent that Cellular Orthopedics is not a “one and done” event. Neither for that matter is a total joint replacement. While skiing in Vail last week, I was in the company of two Sheinkop patient alumni, one a patient under 40 who had undergone Bone Marrow Concentrate hip intervention for advanced osteoarthritis several years ago and one, a 70 year old who had undergone stem cell intervention for his arthritic knees back in 2012. Yes, I take care of friends and they still are speaking to me. Not only do they communicate but, bike and fish with me as well. In both cases as I followed their initial responses, I convinced them of the value of a second procedure and in both cases, it really worked. The younger Sheinkop alumnus is a boarder, the older, a skier. Nevertheless in both cases, they are still extremely active in spite of advanced arthritis in major joints. Might only one stem cell intervention be necessary if I could treat you earlier in the arthritic process? That’s to be determined by ongoing clinical surveillance. The important issue is that both individuals are examples of the potential of Bone Marrow Aspirate Concentrate. There are many more and in the coming days I will Blog about statistically significant Outcomes as I prepare my speeches and manuscripts. Incidentally, while skiing in Vail last week, I happened to change the channel from a sporting even to the movie, Casablanca. Truly, one of the greatest movies of all time; of the great quotes was Rick Blaine’s “here’s looking at you kid” (Humphrey Bogart). What really caught my attention in addition to Ilsa Lund (Ingrid Bergman) was her quote “Play it once, Sam. For old times’ sake”.

How do the stem cells work? It may not just be the stem cells that make a difference in an arthritic joint. We now know that Bone Marrow contains in addition to stem cells, two other major areas of benefit, Growth Factors and Cytokines. While the Adult Mesenchymal Stem Cell may help regenerate cartilage damaged by injury and arthritis, it is the Growth factors and Cytokines that also play an equally important role in the anti-inflammatory effect and reversal of the arthritic process. What happens when we concentrate and prepare the Bone Marrow and execute the Cellular Orthopedic intervention following the Regenexx algorithm of care is reversal or at least a slowing of the arthritic process, a diminution of pain, an improved functional capacity and a delay, maybe avoidance, of a total joint replacement. While there still may be a need for an occasional Tylenol after a BMAC/Stem Cell intervention, you have a good chance of joining me as an alumnus on the slopes, on the bike, wading up a trout stream, or in a fitness pursuit. As well, we may have to do it again in a year or two; but I have yet to record a complication. “Play it once, Sam. For old times’ sake” or in the stem cell world, play it again Dr. Sheinkop to keep me going.

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