You have probably learned about RNA therapeutics over the past several years; most likely you have used this new kind of treatment as both Pfizer/BioNTech and Moderna’s COVID-19 vaccines are mRNA therapies.
RNA therapeutics is a rapidly expanding class of drugs that target pathways making personalized care a reality. They may and are revolutionizing the treatment of many ailments including arthritis. Until recently, Regenerative Medicine has been making use of Messenger RNA (mRNA) without fully understanding that Adult Mesenchymal Stem Cell and the Platelet Rich Plasma act in part through their respective mRNA content. Hence, it is the MSCs found in bone marrow (MSCs) and adipose tissue/fat (SVF) producing Extracellular Vesicles and Exosomes containing the mRNA that are responsible for effecting regeneration. They also may block and reverse the inflammation in your joints responsible for pain and altered function. The same may be said about the Platelets circulating in your blood or contained in your bone marrow. When I perform a Bone Marrow Concentrate joint injection, the benefit in part is the result of mRNA contained in Extracellular Vesicles and Exosomes produced by MSCs. The same may be said when I complete a vena puncture, concentrate the Platelets, and inject the PRP into your joints or soft tissues.
What comes next? Call (847) 390-7666 to schedule an appointment. I will perform a complete orthopedic intake with my team, evaluate your images, and make a recommendation for the treatment of your arthritic joint. Treatment option recommendations, after the intake and review of images, include four different proprietary options for generic Platelet Rich Plasma; Bone Marrow Concentrate (Stem Cells); and the Extracellular Vesicles recovered from your circulating blood that I introduced earlier in this blog. As far as the Adipose Based Stem Cell Trial (Stromal Vascular Fraction), I am anxiously waiting to learn from Personalized Stem Cells www.PersonalizedStemCells.com when the FDA will allow us to begin patient recruitment. Then there is the Collagen Allograft option for those with structural defects to their articular cartilage. Have Questions? Ask.
I gave the reader a lot to process in this blog. To clarify, visit www.sheinkopmd.com or call for that appointment (847) 390-7666.