Cellular Orthopedics Blog
What Can Be, and What Might Have Been, With Your Stem Cells
12 days ago, on a Saturday morning, I received a call from a friend of 67 years, who left a voicemail asking me to call him. We had first met while playing 16-inch softball against each other on Chicago Park District softball diamonds. Last night, at 10:20 pm, his...
Personalized Stem Cell 2020 Review and 2021 Forecast
“I am sitting here at the office, just finishing the first draft of the clinical study report for PSC-CP-001. I am deeply moved and grateful for the incredible efforts you have all made in advising, enrolling patients, completing data forms, monitoring, and all...
Recovery following a Stem Cell Procedure for Arthritis
“Hello, I thought you would like to know that my stem cell in my left knee has worked. I didn't expect it to take so long but I have had little to no pain for the past two months. Thank you all again for your care and please advise your patients to be patient! If...
Might Cellular Therapies Postpone or Prevent Osteoarthritis After Knee Surgery or Injury
Following injury to the articular surface of the knee, measurable changes in the joint microenvironment can occur, including altered expression of proinflammatory cytokines, matrix metalloproteinases (MMPs), aggrecanases, growth factors, and apoptotic factors. A study...
The Stem Cell Facts Speak for Themselves
The feeling? Absolute terror! So many things I thought I could never do again. Walking a mile? It took everything I had to walk 10 feet! Walking on uneven ground? I”ll never be able to do that again! Stairs? Like Mountain climbing with only one leg. Even getting up...
How Might Activity Bolster Cartilage
Can Activity Bolster Cartilage? It may even delay arthritis and influence cartilage healing. Could running actually be good for your knees, hips, and back? Cartilage, which doesn’t have a blood supply of its own, is generally thought to not have the ability to repair...
Current Evidence Based Orthobiologics and Stem Cell Care for The Musculoskeletal System
Tono-Bungay by H.G. Wells, tells the story of a miraculous cure-all, Tono-Bungay, that is in fact nothing other than a pleasant-tasting liquid with no positive effects. Nonetheless, when the young George Ponderevo is employed by his uncle Edward to help market this...
The New World of Cell Based Therapy and Orthobiologics
About 15 years ago, an article was published regarding the use of Platelet Rich Plasma for the treatment of arthritis. Prior to that clinical trial, physicians would use hyaluronic acid (rooster comb) in an attempt to diminish the symptoms from an arthritic joint. The...
The New World of Cell Therapy and Orthobiologics: A Needle and Not a Knife, Part 1
My goal is to separate fact from fiction by delivering evidence-based care specifically related to orthobiologics, and contribute to biologics knowledge and application in arthritis and orthopedic conditions. At present, too many patients are navigating the field...
Mesenchymal Stem Cell Treatment Update for Arthritis
There are two clinical, readily available sources of adult mesenchymal stem cells, to the cellular orthopedist; the musculoskeletal building cells that have the potential to stop the progression of arthritis. These cells may reverse the damage, regenerate cartilage,...
Several Unorthodox Requests for Biologic Treatment of Arthritis
Over the past several weeks, patients have presented with interest in biologic treatment of arthritis other than “can you regrow my cartilage?” While cartilage regeneration was initially marketed by stem cell purveyors, it never made physiologic sense unless the...
Regenerative Medicine Fact Check or Cellular Orthopedic Q&A
Question: Dr. Sheinkop, three months ago you did an A2M intervention on a 72- year old athletic man with progressive limitations from an arthritic knee. You reported how he was doing at six weeks, how is he doing at 12 weeks? Answer: Hi. I trust all is well with...